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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NBEAL2
All Species:
6.67
Human Site:
S2421
Identified Species:
13.33
UniProt:
Q6ZNJ1
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZNJ1
NP_055990.1
2754
302517
S2421
S
G
L
L
G
T
H
S
W
L
P
Y
D
R
N
Chimpanzee
Pan troglodytes
XP_525997
2750
313008
G2416
N
Y
V
I
G
T
H
G
W
L
P
Y
D
R
N
Rhesus Macaque
Macaca mulatta
XP_001094456
2295
260424
A1970
L
F
V
V
S
H
D
A
K
L
L
F
S
A
G
Dog
Lupus familis
XP_541900
2305
251162
S1980
P
K
M
Q
R
L
L
S
G
P
W
V
P
E
S
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZQA0
2742
301906
T2409
S
G
L
L
G
T
H
T
W
L
P
Y
D
R
N
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508701
2269
259447
A1944
R
Y
N
L
R
R
S
A
L
E
I
F
L
I
D
Chicken
Gallus gallus
XP_421964
2298
259902
K1973
H
G
W
L
P
Y
D
K
N
I
S
N
Y
F
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W4E2
3584
396477
E3074
D
V
K
E
L
I
P
E
W
Y
F
L
P
E
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19317
2507
281187
S2181
A
S
Q
R
S
A
L
S
M
D
P
S
N
A
E
Sea Urchin
Strong. purpuratus
XP_785921
3355
375569
W3020
G
V
V
G
T
H
S
W
L
P
Y
D
K
S
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_182078
2946
321916
G2587
T
P
F
L
F
H
H
G
K
A
T
T
T
S
T
Baker's Yeast
Sacchar. cerevisiae
P25356
2167
250854
C1842
P
H
P
E
K
I
A
C
N
V
Q
Q
L
T
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47.1
40.2
74.6
N.A.
88
N.A.
N.A.
39.7
40.6
N.A.
N.A.
N.A.
20.7
N.A.
21.1
33.4
Protein Similarity:
100
65.6
56.3
77.1
N.A.
92
N.A.
N.A.
53.8
55.7
N.A.
N.A.
N.A.
36.1
N.A.
37.4
48.8
P-Site Identity:
100
66.6
6.6
6.6
N.A.
93.3
N.A.
N.A.
6.6
13.3
N.A.
N.A.
N.A.
6.6
N.A.
13.3
0
P-Site Similarity:
100
86.6
33.3
20
N.A.
100
N.A.
N.A.
26.6
20
N.A.
N.A.
N.A.
6.6
N.A.
26.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.6
20.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.5
36.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
9
9
17
0
9
0
0
0
17
0
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
0
0
17
0
0
9
0
9
25
0
9
% D
% Glu:
0
0
0
17
0
0
0
9
0
9
0
0
0
17
9
% E
% Phe:
0
9
9
0
9
0
0
0
0
0
9
17
0
9
0
% F
% Gly:
9
25
0
9
25
0
0
17
9
0
0
0
0
0
9
% G
% His:
9
9
0
0
0
25
34
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
0
17
0
0
0
9
9
0
0
9
9
% I
% Lys:
0
9
9
0
9
0
0
9
17
0
0
0
9
0
0
% K
% Leu:
9
0
17
42
9
9
17
0
17
34
9
9
17
0
0
% L
% Met:
0
0
9
0
0
0
0
0
9
0
0
0
0
0
9
% M
% Asn:
9
0
9
0
0
0
0
0
17
0
0
9
9
0
25
% N
% Pro:
17
9
9
0
9
0
9
0
0
17
34
0
17
0
0
% P
% Gln:
0
0
9
9
0
0
0
0
0
0
9
9
0
0
0
% Q
% Arg:
9
0
0
9
17
9
0
0
0
0
0
0
0
25
0
% R
% Ser:
17
9
0
0
17
0
17
25
0
0
9
9
9
17
9
% S
% Thr:
9
0
0
0
9
25
0
9
0
0
9
9
9
9
25
% T
% Val:
0
17
25
9
0
0
0
0
0
9
0
9
0
0
0
% V
% Trp:
0
0
9
0
0
0
0
9
34
0
9
0
0
0
0
% W
% Tyr:
0
17
0
0
0
9
0
0
0
9
9
25
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _